Detectives believe 14-year-old Dyanah Amaya was in danger on Friday evening, according to the Miami Police Department.
Her mom, Marisol Amaya, told police officers that the teenage girl vanished about 2 p.m.
Officer Christopher Bess said Dyanah was last seen about at 1871 NW 21 Street, in Miami's Allapattah neighborhood.
Amaya is 5-foot-3-inches tall and weighs about 140 pounds. She has brown eyes and brown hair. Bess said she was last seen wearing a black spaghetti shirt, gray basketball shorts and black and white Adidas sneakers.
Bess was asking anyone with information to call 305-603-6300 or 305-603-6310.